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Between 1997 and 2011, extra than two hundred new materials had been notified through the early-caution machine, with the file range of forty nine novel molecules suggested in 2011. The pattern of acute toxicity associated with the consumption of these new substances is commonly similar to that seen with conventional drugs of abuse. Recently, a new class of synthetic stimulants closely associated with pyrrolidine and piperidine compounds and known as pipradrol derivatives appeared inside the leisure drug market. These materials, generating amphetamine-like outcomes, are used by human beings in substitution of conventional illicit capsules. The aim of this paper is to summarize the clinical, pharmacological and toxicological data currently available about this new magnificence of synthetic pills of abuse.
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